_63.png)
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_04_DMpreB_versus_WTpreB.phenotype_DMpreB_versus_WTpreB.cls #DMpreB_versus_WTpreB |
| Phenotype | phenotype_DMpreB_versus_WTpreB.cls#DMpreB_versus_WTpreB |
| Upregulated in class | WTpreB |
| GeneSet | NCI_SIGNALING EVENTS MEDIATED BY STEM CELL FACTOR RECEPTOR (C-KIT) |
| Enrichment Score (ES) | -0.8168748 |
| Normalized Enrichment Score (NES) | -1.8296583 |
| Nominal p-value | 0.0024271845 |
| FDR q-value | 0.0024580609 |
| FWER p-Value | 0.0020 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | MAPK8 | 6459 | 1644 | 2.061 | -0.0613 | No | ||
| 2 | HRAS | 4868 | 2610 | 0.906 | -0.1012 | No | ||
| 3 | SHC1 | 9813 9812 5430 | 3936 | 0.225 | -0.1696 | No | ||
| 4 | AKT1 | 8568 | 4218 | 0.183 | -0.1823 | No | ||
| 5 | SPRED2 | 8539 4332 | 4238 | 0.180 | -0.1810 | No | ||
| 6 | BCL2 | 8651 3928 13864 4435 981 4062 13863 4027 | 4380 | 0.162 | -0.1864 | No | ||
| 7 | GRAP2 | 5113 9398 | 6102 | 0.063 | -0.2783 | No | ||
| 8 | KIT | 16823 | 6209 | 0.060 | -0.2832 | No | ||
| 9 | SPRED1 | 4331 | 6232 | 0.060 | -0.2836 | No | ||
| 10 | GRB10 | 4799 | 8036 | 0.024 | -0.3804 | No | ||
| 11 | PTPN11 | 5326 16391 9660 | 9360 | 0.007 | -0.4515 | No | ||
| 12 | SNAI2 | 22848 | 9750 | 0.002 | -0.4724 | No | ||
| 13 | FOXO3 | 19782 3402 | 10283 | -0.004 | -0.5010 | No | ||
| 14 | LYN | 16281 | 10463 | -0.007 | -0.5106 | No | ||
| 15 | PTPRO | 1093 17256 | 10878 | -0.012 | -0.5327 | No | ||
| 16 | MATK | 3425 19930 | 11601 | -0.023 | -0.5713 | No | ||
| 17 | EPO | 8911 | 11716 | -0.025 | -0.5771 | No | ||
| 18 | MITF | 17349 | 11903 | -0.028 | -0.5867 | No | ||
| 19 | DOK1 | 17104 1018 1177 | 12045 | -0.031 | -0.5939 | No | ||
| 20 | PIK3R1 | 3170 | 12502 | -0.041 | -0.6179 | No | ||
| 21 | SOS1 | 5476 | 13046 | -0.056 | -0.6464 | No | ||
| 22 | PIK3CA | 9562 | 13540 | -0.075 | -0.6720 | No | ||
| 23 | EPOR | 19204 | 13811 | -0.089 | -0.6853 | No | ||
| 24 | KITLG | 19889 3342 | 13917 | -0.096 | -0.6897 | No | ||
| 25 | CBL | 19154 | 14602 | -0.166 | -0.7244 | No | ||
| 26 | MAP2K2 | 19933 | 14908 | -0.221 | -0.7379 | No | ||
| 27 | SH2B3 | 5001 16383 | 15004 | -0.240 | -0.7398 | No | ||
| 28 | JAK2 | 23893 9197 3706 | 15111 | -0.267 | -0.7420 | No | ||
| 29 | STAT5A | 20664 | 15113 | -0.268 | -0.7385 | No | ||
| 30 | MAP2K1 | 19082 | 15318 | -0.325 | -0.7452 | No | ||
| 31 | RPS6KB1 | 7815 1207 13040 | 15722 | -0.503 | -0.7602 | No | ||
| 32 | MAP4K1 | 18313 | 16775 | -1.624 | -0.7954 | Yes | ||
| 33 | MAPK3 | 6458 11170 | 16931 | -1.809 | -0.7798 | Yes | ||
| 34 | RAF1 | 17035 | 17131 | -2.125 | -0.7624 | Yes | ||
| 35 | TEC | 16514 | 17287 | -2.394 | -0.7391 | Yes | ||
| 36 | BAD | 24000 | 17524 | -2.914 | -0.7132 | Yes | ||
| 37 | CRKL | 4560 | 17588 | -3.053 | -0.6762 | Yes | ||
| 38 | GRB2 | 20149 | 17590 | -3.055 | -0.6359 | Yes | ||
| 39 | GSK3B | 22761 | 17596 | -3.078 | -0.5954 | Yes | ||
| 40 | SOCS1 | 4522 | 17793 | -3.598 | -0.5584 | Yes | ||
| 41 | CREBBP | 22682 8783 | 17993 | -4.203 | -0.5135 | Yes | ||
| 42 | VAV1 | 23173 | 18136 | -4.751 | -0.4583 | Yes | ||
| 43 | PTEN | 5305 | 18200 | -4.996 | -0.3956 | Yes | ||
| 44 | GAB1 | 18828 | 18283 | -5.430 | -0.3282 | Yes | ||
| 45 | STAT1 | 3936 5524 | 18294 | -5.505 | -0.2559 | Yes | ||
| 46 | PDPK1 | 23097 | 18324 | -5.661 | -0.1825 | Yes | ||
| 47 | STAT3 | 5525 9906 | 18455 | -6.760 | -0.1001 | Yes | ||
| 48 | PTPN6 | 17002 | 18561 | -8.216 | 0.0030 | Yes |
_64.png)
